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Molecular Effects of Smoking
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Molecular Effects of Smoking
Carcinogens and the Cell Cycle

Grades 6-9

Students explore the important biological concepts of DNA structure
and protein function, by looking at the molecular effects of exposure
to the chemicals in tobacco smoke. Students examine the interaction
of the carcinogen, benzopyrene, with DNA and its mutagenic effect
on protein structure through model building and analysis of a mutagen
database. Students also have the opportunity to observe the effect
of tobacco chemicals on invertebrates behavior. This class can be
expanded into multiple sessions which can include looking at cancer
and the control of the cell cycle through role play, looking at the
inheritance of a cancer gene, exploring the effects of smoke on fetal
development, and the effect of nicotine on the function of the nervous

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Wisconsin State Standards

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